Abstract

A COMPARATIVE STUDY OF PARACETAMOL VS DICLOFENAC SODIUM FOR POST-OPERATIVE PAIN RELIEF IN LAPAROSCOPIC APPENDECTOMY -STUDY AT A TERTIARY CARE CENTRE

Dr. Harshavardhan K., Dr. Rithesh D. Cunha, Dr. Reshmina Chandni Clara Dsouza*, Dr. Paramanand Reddy

Abstract

Background and Objective: Appendicitis most often treated with a combination of surgery and antibiotics. Although the magnitude of pain can be expected to be reduced when compared to open procedures, pain may still be a significant factor during the postoperative recovery period following laparoscopic surgery. Recently paracetamol has been launched as an an injectable and is popular as an postoperative analgesic as among surgeons. Diclofenac is an acetic acid derivative non-steroidal anti-inflammatory with analgesic properties These two drugs are cost-effective, easily available, and also very few studies are available comparing these two drugs. In view of the above said we are conducted a study which compared paracetamol 10 versus diclofenac 1.5 mg/kg IM for postoperative pain relief in laparoscopic appendectomy. Materials and Methods: After obtaining approval from hospital academics and ethics committee prospective, randomized, double blind, comparative study was conducted between the time period1st December 2018 to 30th march 2020 at father muller medical college hospital. 100 consenting patients who underwent laparoscopic appendectomy who met a pre-defined inclusion criteria and exclusion criteria were included the study and were assessed for the effects of diclofenac and paracetamol for post-operative pain management. Each group received either paracetamol 10 mg/kg IV or diclofenac 1.5 mg/kg IM. Visual analogue scale was explained to the patient preoperatively. Vital parameters was checked and recorded preoperatively. Monitoring was done every 1 hourly for the first 3 hours and then every 6 hourly for next 24 hours. Results and Observations: The mean heart rate, mean diastolic blood pressure, mean systolic blood pressure was more in the diclofenac group suggesting that pain was observed more in the diclofenac group at all times, at all times there was statistical significance with p value

Keywords: Analgesic, Paracetamol, Diclofenac.