Abstract

A REVIEW - SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS)

Tamnar Sachin Maruti*, Kisan Bobe, Dr. Vaishali Potnis, Suchita Dhamane and Pote Vishal Suresh

Abstract

The Drug Delivery System (SNEDDS) is a new drug delivery system to improve the water solubility of water-soluble drugs. It is an isotropic mixture of oil, surfactant, cosurretive molecules, and also contains cosolvent molecules. It is the system of Drug Administration is thermodynamically and kinetically stable. The system of Drug Administration with mild agitation is followed by dilution of aqueous media such as GI liquid and stable Nano emulsion can O / W. Having the size of the blood cells is less than 100 nm. It is an important type of drug delivery system to maintain chemical stability as well as drug solubility. Self- Nanoemulsifying drug delivery system (SNEDDS) is an important application in Class II and IV BCS drugs to improve water solubility of water-poor drugs. It is important to prevent the interfacial tension and improving the dissolution as well as absorption rate of drug molecule. It is Novel Drug Delivery System is Applicable for parenteral, Ophthalmic, intranasal and cosmetic drug delivery system. And the present review describes Preparation, components, mechanism, of self-Nano emulsification, biopharmaceutical aspects, characterization methods and applications of self-Nanoemulsifying drug delivery system (SNEDDS) For Enhancement of oral Bioavailability of poorly water soluble drugs.

Keywords: Nano emulsion, Mini emulsion, Submicron emulsion, Surfactant, Selfemulsifying system and Psedoternary Phase.