Abstract

AN INSIGHT INTO THE COVID-19: A CORONAVIRUS INFECTION IN HUMANS

*Jadon S. Arvind, Bhadauriya Poonam and Sharma Manoj

Abstract

There is a new public health crises caused by a 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. The COVID-19 has been diagnosed as the cause of an outbreak of severe pneumonia or respiratory illness in Wuhan, Hubei Province, China beginning in month of December 2019. As per report of World Health Organization till 01 May 2020, this epidemic had spread to 212 countries or territories with 3,614,702 confirmed cases, including 2,50,220 deaths. On 30 January 2020, World Health Organization officially declared the COVID-19 epidemic as a public health emergency of international concern. The clinical symptoms of COVID-19 patients include mild to moderate respiratory illness and a small population of patients appeared gastrointestinal infection symptoms. The elderly and people with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease and cancer are susceptible to infection and prone to serious outcomes, which may be associated with acute respiratory distress syndrome (ARDS). At present, there are no specific vaccines or drugs for the treatment of COVID-19. However, there are many ongoing clinical trials evaluating potential treatments and several potent candidates of antivirals and repurposed drugs are under urgent investigation. In this review, we summarized the origin, spread, latest research progress, diagnosis methods, pathogenesis, symptoms and clinical characteristics of COVID-19 and also discussed the currently available treatment and scientific advancements to combat the novel corona virus.

Keywords: COVID-19, SARS-CoV-2, Novel Corona Virus, Pandemic, 2019-nCOV.