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Abstract

EMERGING PHAACEUTICAL APPLICATIONS OF PIPERIDINE, PYRROLIDINE AND IT S DERIVATIES

Shazia Haider, Zafar Saeed Saify*, Nasreen Begum, Seema Ashraf and  TabindaZarreen,S.M.Ghufran Saeed

Abstract

Heterocyclic compounds form largest classical division of organic chemistry by gaining enormous importance in industry and biology. . The mainstream of pharmaceuticals is heterocyclic. Numerous modifiers and stabilizers used in different industrial applications such as cosmetics, information storage, plastics, optics, electronics and reprography along with biologically active agrochemicals are heterocyclic in nature. Pyrrolidine and piperidine both secondary amines are members of saturated heterocyclic compounds demands main cause of interest for chemists, biologist and pharmacist due to their significant and diverse range of promising biological activities like analgesic, anti-inflammatory, CNS, antioxidant, antihistaminic, cytotoxic, antimicrobial and others from last few decades. In the present review we attempts to give information about the synthesis and biological activities of various kinds of Pyrrolidine and piperidine derivatives which might be helpful for both pharmaceutical and chemist in further research.

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