COMPARATIVE CLINICAL STUDY OF AYURVEDIC TREATMENT AND CONVENTIONAL STANDARD TREATMENT IN THE MANAGEMENT OF ARDHAVABHEDAKA (MIGRAINE)-A RANDOMIZED CONTROLLED TRIAL
Shweta Mata*, Shivshankar Rajput, Hiten Maniar and D. B. Vaghela
Abstract
Background: Ardhavabhedaka-hemicranial headache is a common
disease that affects millions of individuals worldwide. The pain may be
very bad and hurt so much that a person may have a hard time doing
anything. The survey results suggested that both patients and
physicians believe migraine treatment is elusive and that patients are
becoming increasingly frustrated and dissatisfied with treatment
outcomes. Ardhavabhedaka is a Tridoshaja and Vata kaphaja
dominant disease according to Acharya Sushrut and Acharya Charak
respectively. Its diagnosis is based on mainly clinical history. Material
and Methods: In this study, eligible 107 patients were selected and
randomly divided in two groups through computer generated
randomization. Laghu Sutashekhara Rasa orally and Brihat
Dashmoola Taila Nasya were given in trial group and Tab. Flunarizine was given in control
group for 60 days. The primary outcomes measured were percentage changes in chief
complaints, associate complaints and MIDAS of Ardhavabhedaka in comparison to both
groups. Results: Regarding effect of therapy on Chief complaints in trial group, 83.21%
relief was found in severity of headache, 82.53% in duration of headache and 82.06% in
frequency of headache. In control group, 83.02% relief was found in severity of headache, 82.61% in duration of headache and 82.29% in frequency of headache. In MIDAS, 64.14% and 48.04% improvement was found in trial group and control group respectively. No any adverse drug reaction was found during whole study. Conclusion: Overall assessment of the therapy showed that administration of Laghu Sutashekhara Rasa and Nasya with Brihat Dashamoola Taila provided statistically significant improvement on subjective and MIDAS criteria.
Keywords: Ardhavabhedaka, Brihat Dashamoola Taila, Laghu Sutashekhara Rasa, Migraine.
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