Abstract

A REVIEW ON NEWLY SYNTHESIZE PYRAZOLE BASED COMPOUNDS & IT’S PHARMACOLOGICAL ACTIVITY

Jaiswal Shivam*, Gupta Kumar Sujeet, BhumikaYogi, Rudrapratap Singh, Ram Sevak Varma and Amitdiwedi

Abstract

Pyrazole is a hetero cyclic with five member ring compound it has minimum one hetero atom like O,S,N. Pyrazole is multilateral lead compound for designing new biological activities of compound by modification of substitute of pyrazole like Bactericidal, Fungicidal, Anticonvalsant, Antiviral, Anti-inflammatory, Anti diabetic, Anticancer, Anti-tumor, Anti-microbial & Carbonic anhydrase an Acetylcholinesterase inhibitors Activities by using of different bioassay. All pyrazole derivatives determine via different spectrometrical methods such that Ultra-violet, Infra-red, FTIR, NMR, MASS spectrometric technique and identified the different compounds and their different biological activity. In this article described many model such that carragennan induced rat paw edema model and also describe the more potent compounds structure. Given data describe that pyrazole being five memebered heterocyclic have pharmacological action. Result of various derivaties of various substitute pyrazole are reviewed in present article. Different types methods for synthesizing pyrazole derivatives and pharmacological action are discussed after studying many research paper.

Keywords: Pyrazole, Antiinflammatory, Antibacterial, AntiDiabetic, Antitumor, Antiviral, Anti cancer.