Abstract

A REVIEW ON THIAZOLE BASED COMPOUNDS & IT’S PHARMACOLOGICAL ACTIVITIES

Ram Sevak Verma*, Sujeet Kumar Gupta, Shivam Jaiswal and Amit Kumar Dwivedi

Abstract

Thiazole is a heterocyclic five members ring that contains sulfur and nitrogen both hetero atoms in a whole cyclic structure. The thiazole nucleus assumes a significant job in medicinal chemistry to synthesize and design a series of multiple biologically active derivatives such as anticancer, antibacterial, antimalarial, antituberculosis, antidiabetic, anticonvulsant, anticandidal, antiviral, aldose reductase inhibitor, a cardiotonic PDE3 inhibitor, and antioxidant. Thiazoles used effectively and furthermore it is a non-cancer-causing in nature. The main motto of this review article refers to describe various pharmacological activities and their pharmacological action against different types of bacteria using different types of models (such as MES test, Vitro assay, Vivo assay, and Shinji’s method) these methodologies may give important data to the further structure of more dynamic natural specialists through different alteration and derivatizations. The thiazole moiety is widely recognized in heterocyclic science and in sedate structure. Thiazole subsidiaries are generally utilized as bioactive specialists. The inspiring atomic design of thiazoles constructs them reasonable moieties to medicate improvement. That mentioned investigation data of our topic to substantiate the ongoing information accessible via different engineered techniques & characteristic features of thiazole subordinates.

Keywords: Thiazole, Anticancer, Antioxidant, Antimalarial, Antiviral, Anticonvulsant.