Abstract

A REVIEW ON VARIOUS PHARMACOLOGICAL ACTIVITY OF NEWLY SYNTHESIZED CARBAZOLE MOIETIES

Amit Kumar Dwivedi*, Sujeet Kumar Gupta and Ram Sevak Verma

Abstract

Carbazole is an heterocyclic compound comprise of two- six member ring that it can be merge on both side of five membered ring hold nitrogen atom. The carbazole nucleus plays a important role in medicinal chemistry to synthesized a series of multiple biological active derivatives are anti-inflammatory, Anti-proliferative, Antibacterial, Antidiabetic, Antioxidant, Antifungal, Anticancer. All the carbazole derivatives and substituents are mention in article. These derivative of carbazole are tested for varying pharmacological activities. The main motive of the review article to describe their pharmacological action and activities against different type of bacteria using different type of models(in vitro assay, in vivo assay etc). Different types methods for synthesizing carbazole derivatives and pharmacological action are discussed.

Keywords: Carbazole, Anti-cancer, Antibacterial activity, Antimicrobial, Antifungal, Anti-HIV activity.