Abstract

A CASE REPORT ON FLUMINANT LEPTOSPIROSIS WITH HEPATORENAL INVOLVEMENT

Tasneem Abdul Gafoor**, Ajeena Anto*, Shahina K. P.* and Manju Mohan*

Abstract

Leptospirosis is an important zoonotic disease humans and animals that are caused by pathogenic spirochetes of the genus Leptospira. Leptospirosis is endemic in most areas where dengue virus is transmitted and may be mistaken for dengue, which is typically more common. Leptospirosis has protean manifestations ranging from a flulike illness to fulminant hepatic and renal failure culminating in death. A 40 years old male patient came with complaints of fever and myalgia for past 4 days. He had history of yellowish discoloration of skin and sclera, decreased urine output, malena and petecheial rashes all over the body for past 2 days. On examination the patient was febrile, icteric and petecheial rashes were seen. The investigation parameters showed high levels of ESR, Blood urea, LFT, Creatinine and Leptospira AB IgM – positive. The patient was treated with INJ. CEFTRIAXONE, T.DOXICYCILLINE, T.BILASTINE, T.ACETAMINOPHEN, and T.CILNIDIPINE. After the 10 days of treatment in hospital the patient was discharged as he was symptomatically improved. Leptospirosis should be diagnosed as early as possible since early antibiotics are beneficial in the treatment.

Keywords: Leptospirosis, zoonotic, spirochetes, fulminant, malena, petecheial, icteric.