Abstract

TO CORRELATE THE ASSOCIATION OF THYROIDISM WITH CARCINOMA OF BREAST

Divya Panthi, Alibha Rawat, Asha Agarwal, Rupa Guha Nandi and *N. Ganesh

Abstract

Introduction: There are number of diseases that can be associated with developing high risk of breast cancer; notably, among them are: thyroid disorder (thyroidism) and gallbladder stones (cholelithiasis). A number of breast cancer patients are found to have a history of thyroid problems and/or gallbladder stones indicating a possible role of these diseases in the development of breast cancer. The current research work utilizes the dermatoglyphic tool of ATD Measurement; i.e., Angle of Triradius of palmer area by marking the palmer area with lipstick, or ink [pen] to demarcate epidermal ridges and measuring the angle by protractor. Methods -ATD Angle Measurement- ATD angle was measured and then a comparison was done between healthy females and the ones having breast cancer and thyroid problems. Mean ATD Angle Measurement was done in healthy control females, breast cancer females and Thyroid disorder patients. Five Breast Cancer female patients were selected from the hospital registry of JLNCH&RC at random and "atd" angles or axial triradius angles were measured in them along with five healthy control females and five females with thyroid disorders after taking their informed consent and other details such as Medical and Ob/Gyn History and making a Pedigree Chart. Results: The mean "atd" angle of breast cancer patients was found to be 40° and that of Thyroid disorder patients was found to be 39°. Healthy control females on the other hand had a mean atd angle of 36°. Conclusion: The several studies provides insight into the diseases like thyroid disorders and gallbladder stones that can pose high risk for developing breast cancer the mechanism of which is yet to be understood and more studies needs to be done to explain the triggers caused by these diseases that leads to breast carcinogenesis and identification of woman at increased risk for the development of breast cancer. By utilizing this dermatoglyphic tool, the earliest possible diagnosis of breast cancer would be possible by establishing the diseases like thyroid disorders as high risk categories, which in turn would improve the results of breast cancer treatment.

Keywords: Atd angle, Carcinoma Breast. Dermal ridges, Digital patterns, High Risk, triradii, total finger ridge count.