Abstract

PHARMACEUTICAL CO-CRYSTAL: AN METHOD TO ENHANCE THE SOLUBILITY

Shubham D. Udawant*, Amol B. Waghmare, Dr. Ashish Y. Pawar, Dr. Khanderao R. Jadhav

Abstract

Co-crystallization is a method wherein acknowledge the visitor atom inside a cross section alongside pharmaceutical dynamic fixings. A co-crystallization is increasing more enthusiasm for the ongoing time in the field of drug store. Co crystallization gain enthusiasm as well as they improves the bioavailability of medication by changing the physical and substance properties. Co precious stone can be set up from two particles have a particular size or shape and with unequivocal H-holding i.e. hydrogen holding. In the process, for example, co granulating the indistinct phage is produced structure co precious stone. The physiochemical properties of dynamic medication pharmaceutical can be changed by different procedure like micronization, salt development, and formless medication embodiment. Helpless solvency of medication and helpless bioavailability are the primary idea for change and advancement of new medication item which is comparative in real life and have more prominent bioavailability.

Keywords: Solid Based Technique, Solvent Based Strategies, PXRD, Co-Crystal Formation.