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Abstract

EVALUATE THE STABILITY OF MEDHYA CHURNA (AN AYURVEDIC POLY HERBAL DRUG) BY MICROBIOLOGICAL MEASURES IN THE MANAGEMENT OF ATTENTION - DEFICIT / HYPERACTIVITY DISORDER (ADHD) IN CHILDREN

Kingsila Manohari*, Dr. Cholera M. S., Prof. K. S. Patel and Dr. V. K. Kori

Abstract

Background: ADHD is the most common neurodevelopmental, behavioral disorder in childhood characterized by persistent pattern of inattention and /or hyperactivity and impulsivity, it affects 5% of Children all over the world. This disorder is mainly managed by multimodal approach with psychostimulant medicines in modern medical system. There is no exact correlation in Ayurvedic classics to ADHD, but it’s etio-pathogenesis can correlate with Manasa Roga in Ayurveda. Aim: To study the stability of Medhya Churna in different time interval, different climatic conditions, different temperature and different humidity set ups. Materials and Methods: Sample of Medhya Churna was prepared and check the microbial and fungal contamination at different climatic conditions, temperature and humidity from the date of preparation to date of last microbiological study. Results: No any microbial and fungal contaminations was found in microbiological study of Medhya Churna. Discussion: The present study was carried out to observe the stability study of Medhya Churna with respect to Microbial Contamination of sample prepared, stored in different climatic conditions and temperature. Thus a baseline Microbial profile was studied at different interval for total 11 months of period. (i.e. time for consumption of prepared drug). At the end of study, the sample was not showed presence of any Microbes. Conclusion: In microbiological study of the Medhya Churna it was showed that there were not found any growth of bacterial or fungal microorganisms till 20th Feb 2020 i.e. 11 months from the date of preparation, its shows stability and good shelf life of the drug. Hence in the present study the stability test of Medhya Churna with respect to microbiological findings was negative at room temperature, warm and cold, dry and humid conditions.

Keywords: Attention –Deficit /Hyperactivity Disorder(ADHD), Medhya Churna, Microbial contamination.


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