Abstract

A COMPREHENSIVE REVIEW ON: A PLANT CASSIA TORA (FABACEAE) AS ANTIPSORIATIC AGENT

Kale Akshada Sudhakar*, A. N. Aher, Donagre Gauri Shantaram, Band Pranali Sandeep, Chawan Ashwini Ramkrushna and S. R. Gawali

Abstract

Psoriasis is a very common chronic, disfiguring, inflammatory condition of the skin. This problem has a profound psychological impact on lowering self-esteem and interpersonal relationships. This skin disorder is seen worldwide and is thus a matter of serious concern. The prescribed synthetic drugs available in the market for the treatment of psoriasis are associated with different adverse effects, so researchers around the world are searching for new, effective, and safer drugs from natural resources. Many medicinal plants are available in nature and these plants are used for treating skin diseases. Psoriasis is characterized by plaques and patches on the skin. It is an autoimmune disease that involves T helper cells in the pathogenesis of the disease. It manifests inflammatory, scaly red or white silvery flaky skin which may be a fluid-filled lesion with soreness and itchiness. The prevalence rate of psoriasis is increasing day by day and treatment of psoriasis is long term and not completely cures the disease. The plant Cassia tora L. is traditionally claimed to be useful in the treatment of a number of skin diseases, it is a small shrub growing as weed in Asian and African countries. It is known edible leafy vegetable taken up by Asians. It has been Traditionally used in ringworm infection over the years. Leaflet and seed are primary parts used for medicinal purposes. It has found application in Indian and Chinese medicine. The plant Cassia tora L., (Fabaceae), traditionally, is claimed to be useful in the treatment of psoriasis and other skin diseases. The three flavonoids, namely luteolin-7-O-E-glucopyranoside (1), quercetin-3-O-E-Dglucuronide (2) and formononetin-7-O-E-D-glucoside (3), Extracted from cassia tora Linn shows remarkable antipsoriatic activity. The present article includes all the possible formulations prepared from plant cassia tora, useful in treatment of psoriasis. From this review It is concluded that cassia tora has large scope for research on its Antipsoriatic activity and formulation to develop one of the newer, safer, patient acceptable and economical dosage form.

Keywords: Psoriasis, Cassia Tora, Pharmacognosy, Flavonoids, Formulation and Evaluation.