Abstract

PREPARATION, SPECTRAL CHARACTERIZATION, THERMAL STABILITY AND BIOLOGICAL ACTIVITIES OF Mn (II) COMPLEX WITH 2- AMINOBENZONITRILE AND OCTANOATE

R. Govindharaju*, S. Balasubramaniyan, L. Palanivelan, K. Rajasekar& T. Ramachandramoorthy

Abstract

Metal complex of Mn(II) with 2-aminobenzonitrile (ABN) and octanoate ion ligand was synthesized by using microwave irradiation and characterized by the elemental analysis, metal estimation, molar conductance, UV-Visible , IR and Far-IR spectra, non-electrolyte behaviour and monomeric nature of the complex assed from their low molar conductance value. The IR and UV-visible spectra suggest that the complex has Distorted octahedral geometry. The thermo gravimetric analysis of the complex shows the thermal stability of them. The antibacterial and antifungal activities of ligands 2- aminobenzonitrile and sodium octanoate and Mn(II) complex were studied against the following strains of microorganisms E-coli, Enterobacter, Klebsiella, Staphylococcus aureus, Streptococci, Salmonella typhi, P.aeruginosa, C. albicance, Aspergillus Flavus and Aspergillus niger by disc diffusion method. Mn(II) complex show enhanced activity compared with that of free ligand for Klebsiella, Streptococci and P.aeruginosa, organisms at100μg/ml and at 50μg/ml.

Keywords: Mn(II) complex, ABN, Octanoate, Antibacterial, Antifungal.