Abstract

A REVIEW ON AURONES AND THEIR DERIVATIVES AS A RELIABLE THERAPEUTIC AGENT

Sarath Lal P. S.*, Anoob Kumar K. I., Khadeejath Shifania, Rayees N. M., Sulaikha S. and Zainaba Rameeza

Abstract

Aurones constitute a subclass of flavonoids which occur rarely distributed in nature. Chemically, aurones are (Z)-2- benzylidenebenzofuran-3(2H)-ones, exhibit a strong and broad variety of biological activities. Like antifungal, antifeedant, tyrosinase inhibitors, anticancer agent, antimicrobial, antiparasitic, and antioxidants. They are the less common representatives of a flavonoid subclass and not widely exploited. In this review, an attempt has been made to study various novel biological activities and structure activity relationships of several naturally occurring aurones and their synthetic derivatives as a potent lead compound for establish therapeutically active molecules with high efficiency and less severe side effects.

Keywords: Flavonoids, Aurones, Antifungal, Anticancer, Antioxidant.