Abstract

SUCCESSFUL TREATMENT OF CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE WITH COMBINATION OF MEROPENEM & COLISTIN-A CASE REPORT

Apollo James*, Sudhakar.R, Yasaswini B, Minu.k.George, T.R.Ashok kumar,T. Sivakumar

Abstract

One of the most serious problems in global public health today is the increasing incidence of antibiotic resistant bacterial infections, which increases mortality, morbidity, length of the hospital stay and cost of the treatment. Among the enterobacteria harboring Carbapenemaseencoding genes, Klebsiella Pneumoniae is the most common, rapidly become endemic in many hospital settings around the world. Of particular concern, emergence of Enterobacteriaceae that are resistant to Carbapenemes, the class of antibiotics considered being a serious threat which is seen in this case and limited treatment options associated with these organisms. In this we report a case of Carbapenem resistant K.Pneumoniae in a patient diagnosed with Subdural hemorrhage and right lower lobe Pneumonia (Hospital acquired) and who was successfully treated with antimicrobial combination of Meropenem and Colistin.

Keywords: Antibiotic resistant, bacterial infection, K. pneumoniae, Meropenem, Colistin.