Abstract

REVIEW ON DRUGS USED FOR MANAGEMENT OF PRE-DIABETES

Aswin Baiju, N. Venkateswaramurthy* and R. Sambathkumar

Abstract

Pre-diabetes is the condition, which is used to classify patients with irregularly elevated blood glucose, but not asmuch as high to support the diagnosis of diabetes mellitus, but can progress to type 2 diabetes mellitus by life style changes. Lifestyle modifications, clinical advances and pharmacotherapy interventions in benefits have been observed in pre-diabetic individuals have shown the benefits in transformation back to normoglycemia and to diminish the incidence of diabetes. Metformin is the mostly recommended primary pharmacotherapy with lifestyle changes, unless it is contraindicated or not. It enhances the action of insulin bydeclining the amount of hepatic glucose production in the liver and mostly reduces the incidence of pre-diabetes.

Keywords: Pre-diabetes, diabetes mellitus, metformin, lifestyle changes.