Abstract

ROLE OF LIPIDS IN PREVENTION OF MENTAL DISEASES

Rekha Shah*, Hem Raj Vashist and Shivani Dogra

Abstract

Lipids are the naturally occurring compounds which include mainly fats, oils, waxes, and phospholipids. They are obtained from plants and animal's origin. Lipid metabolism plays a significant role in CNS because it originates in higher concentrations. Brain is a central organ of the human body which consist of highest lipids, after adipose tissue. The role of lipids in tissue damage and cell signaling is indicated by varied neurological disorders. The present review aims to give an overview regarding lipids and its imbalances with CNS disorders such as Parkinson's, Schizophrenia, epilepsy, Multiple sclerosis, Alzheimer's disease and CNS injury including traumatic brain injury, stroke, and spinal cord injury. Moreover, the viable mechanisms of altered level of lipids and their metabolites have additionally been discussed in detail.

Keywords: Lipids, Parkinson's disease, lipid peroxidation, CNS injury, Schizophrenia, epilepsy, Multiple sclerosis, Alzheimer's disease, traumatic brain injury, stroke, and spinal cord injury.