Abstract

AN OVERVIEW OF TRANSDERMAL DRUG DELIVERY SYSTEM

R. Suresh*, P. Dhivyabharathi*, Dr. S. Chandra, S. Sangeetha, A. Sheikalisha, B. Nandhini

Abstract

Transdermal drug delivery system (TDDS) is one of the systems lying under the category of controlled drug delivery, in which the aim is to deliver the drug through the skin in a predetermined and controlled rate. An advantage of a transdermal drug delivery route over other types of delivery systems such as oral, topical, intravenous, intramuscular, etc. is that the patch may essentially can provide a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layers of medication embedded in the adhesive. Basic components of TDDS include polymer matrix, membrane, drug, penetration enhancers, pressure sensitive adhesives, backing laminates, release liner, etc. Transdermal patches can be divided into various systems like reservoirsystem, matrix system and micro-reservoir system, which are used to incorporate the active ingredients into the circulatory system via the skin.

Keywords: TDDS, Basic components, types of transdermal patches.