Abstract

AQUASOMES

Jafor Ali, B. V. P. Deepthi*, Ruchi Baherji, P. Harika, B. Vinitha, Dr. JVC Sharma

Abstract

Aquasomes are self assembled structured particles composed of calcium phosphate or ceramic diamond covered with a polyhydroxyl oligomeric film and it is perform as nanoparticulate carrier system. Aquasomes can be considered to the most recently developed drug delivery system for therapeutics as they possess the ability to deliver active molecules such as protein, peptides, hormones, antigens, genes etc. The solid core provides the structural stability, while the carbohydrate coating protects against dehydration and stabilizes the biochemically active molecules. After synthesis of solid center of ceramic and polyhydroxyoligomeric material coating like cellulobiose and trehalose the last stage was drug loading during which the aquasomes perform as host particulates to non-covalently interact with bio-active moiety via hydrogen and cationic bonding.

Keywords: Aquasomes, Self assembled, Calcium phosphate, Nanoparticulates.