Abstract

INVITRO ANTIOXIDANT PROPERTIES OF SIDDHA SASHTHIRIA MEDICINE SANGU CHUNNAM

Dr. V. Indumathy* Dr. S. Sakthikala

Abstract

Chunnam are exclusive Siddha metallic/minerals, Animal's derivative such as horns, shells, feathers grounding and preserved with herbal juice or decoction and exposed for siddha, which are widely recommended for treatment of a variety of chronic ailments. Sangu Chunnam is an animal product Sangu (Bivalvae Shells), which prepared by the methods recommended in the Siddha literature using lemon Juice (Citrus lemon). The physical properties of Sangu Chunnam solubility, colour and pH and Infrared (IR) spectroscopic were analysed. The IR spectrum the functional groups were acknowledged and they are correlated with the curative nature of the drug. Invitro antioxidant activities of Sangu Chunnam were investigated using ABTS assays, lipid peroxidation, metal chelating, nitric oxide scavenging and superoxide scavenging assay. The results confirmed that the Sangu Chunnam synthesized by lemon juice were crystalline in nature. ABTS radical concentration (EC50 15.24 μg/mL), Lipid peroxidation concentration (EC50 18.23 μg/mL), Metal chelating concentration (EC50 16.4 μg/mL), nitric oxide radical concentration (EC5016.63 μg /mL) and superoxide scavenging activity (EC50 19.36 μg/mL) under in vitro conditions. The antioxidant methods confirmed that the Sangu Chunnam have more antioxidant activity as compared to vitamin C. The studied Sangu Chunnam possess considerable antioxidant activities and may contribute to the wellbeing of individuals who possess aging related diseases.

Keywords: Anti Oxidant, Five Methods, Sangu Chunnam, Siddha Preparation, Vitamin-C Enriched.