Abstract

SUB CLINICAL HYPOTHYROIDISM AND CARDIOVASCULAR RISK

*Dr. Sharda Singh, Dr. Mohan Singh, Dr. Lokendra Deo Bhatta and Sujata G. M.

Abstract

Thyroid diseases are common endocrine abnormalities around the world. Thyroid hormones play an important role in regulating different metabolic functions. According to the clinical presentation, hypothyroidism is classified as subclinical, mild and overt. Subclinical hypothyroidism (SCH) has been correlated with cardiovascular system due to its major impact on lipids and blood pressure (BP). There are many studies supporting the fact that patients with hypothyroidism are prone to develop a greater cardiovascular risk especially in the patients with thyroid-stimulating hormone (TSH) >10mU/l and thyroxine therapy should be recommended for these patients. But the association between the sub clinical hypothyroidism and cardiovascular disease is still controversial. Our study will investigate the relation between SCH, CVD and associated mortality. So, the main aim of this narrative review is to assess the thyroid dysfunction i.e. sub clincal hypothyroidism and its impact on cardio vascular system, in order to establish specific preventive recommendations and minimize mortality due to CVD. To accomplish these objectives, an updated search of Google scholar and PubMed was conducted for the most recent articles investigating the SCH and its risk on CVD.

Keywords: Thyroid hormones, Subclinical hypothyroidism, metabolism, Cardiovascular diseases.