Abstract

A REVIEW ON SELF EMULSIFYING DRUG DELIVERY SYSTEM

Miss. Apeksha V. Masal*, Mr. Nilesh A. Nalawade, Miss. Sharayu S. Ranaware, Miss
Akanksha B. Yadav, Miss. Sukanya P. Paricharak, Miss Pallavi G. Dhaware, Miss. Swati B. Kavade

Abstract

Solubility of orally administered drug is a major challenge of pharmaceutical industry as nearly 35 to 40% of newly launched drug passes low aqueous solubility which leads to there are having poor dissolution and low bioavailability. This can be increased by different methods like salt formation, solid dispersion and complex formation. Self Emulsifying Drug Delivery System (SEDDS) is gaining popularity for improving the solubility of lipophilic drugs. SEDDS are defined as isotropic mixtures of one or more hydrophilic solvent/ and co- solvent surfactants that have a unique ability of forming fine oil -in- water (o/w) micro emulsion upon mild agitation followed by dilution in aqueous media, such as GI fluids. Present review article provides a compressive knowledge and updated account of advancements in SEDDS with regard to its composition of excipients, various methods of solidification of liquid SEDDS, and also various Pharmaceutical advantages.

Keywords: Micro emulsion, Drug.