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Abstract

A REVIEW ON DEVELOPED AND VALIDATED METHOD FOR MONTELUKAST SODIUM AND BILASTINE FROM PURE AND IT’S PHARMACEUTICAL DOSAGE FORM

Annasaheb R. Kudhekar*, Nachiket S. Dighe and Amol S. Dighe

Abstract

Nowadays, many anti-allergic drugs are emerging in the market. One of them is combination of Montelukast Sodium and Bilastine. Both are different in their mode of action. Montelukast Sodium is a leukotriene receptor antagonist and Bilastine is a selective histamine H1 receptor antagonist. The aim of this article is to study the previously reported various analytical techniques for the determination of Montelukast Sodium and Bilastine. There are various techniques for estimation of drug such as RP-HPLC, UV spectroscopy, MS, etc. The RP-HPLC is the most accurate and easy method for estimation.

Keywords: Montelukast Sodium, Bilastine, RP-HPLC, etc.


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