Abstract

A COMPREHENSIVE REVIEW OF MICROSPHERES AND ITS USES IN CANCER TREATMENT

Vasu Rajan* and Jasu Rajan*

Abstract

Microspheres are small free-flowing particles with 1-1000um diameter and can be used to overcome the problems of conventional drug delivery. By altering the materials, methods, and polymers the therapeutic efficacy of microspheres containing drug content can be altered. We have discussed about microspheres, their various types, techniques used to manufacture microspheres, also about the advantages and disadvantages of microspheres, how microspheres are used in the treatment of different types of cancers. Cancer microsphere technology is the latest form of cancer treatment. Cancer is a disease in which cells are abnormal they are the same as normal cells, with just a minute change in genetics or function. The main disadvantage of anticancer drugs is their lack of selectivity, which causes serious side effects and leads to reduction in effectiveness of treatment. As it is very difficult to treat abnormal cells in the normal way of conventional drug delivery system. Microsphere technology is perhaps the only method that can be used for site-specific action, without causing adverse effects on normal cells. Various microspheres that are designed or programmed to take advantage of microsphere technology in targeted drug delivery for treatment for various cancers. We have looked at the help of microspheres as a cancer treatment tool.

Keywords: Microspheres, cancer therapy, types of microspheres, methods to prepare microspheres.