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Abstract

NOVEL TREATMENTS AND FUTURE PROSPECTS FOR BRAIN TUMOR BY USING NANOTECHNOLOGY: A REVIEW

Anchal Verma* and Argha Bhowmick*

Abstract

The central nervous system (CNS), consisting of the brain, medulla spinals, and retina, superintends to the acquisition, integration and process of peripheral data to properly coordinate the activities of the full body. Neurodegenerative and neurodevelopmental disorders, trauma, stroke, and brain tumors will dramatically have an effect on central nervous system functions leading to serious and life-long disabilities. Globally, the social group and economic burden related to central nervous system disorders continues to grow with the ageing of the population so exacting for simpler and definitive treatments. Glioblastoma Multiform (GBM) is one the foremost common intracranial tumors discovered by Burns (1800) and Abernethy (1804) supported gross morphology of the autopsied material and said as ―medullary sarcoma‖ and later ―fungus medullary‖. This review summarizes new developments on pathophysiological aspects of GBM and novel therapeutic methods by victimization engineering to boost quality of lifetime of patients. These novel therapeutic approaches suppose increased penetration of drug medical care into the growth tissues by use of nanomedicine for each the diagnostic and therapeutic functions, observed as ―theranostic nanomedicine‖. Although, the barrier (BBB) is fenestrated round the outer boundary of the growth tissues, the BBB continues to be tight inside the deeper tissues of the growth. Thus, drug delivery could be a challenge for gliomas and needs new therapeutic advances.

Keywords: central nervous system; brain tumor; glioblastoma multiform; eurodevelopmental disorders; nanotechnology.


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