Abstract

EVALUATION OF THROMBOLYTIC ACTIVITY IN JUSTICIA TRAQUEBARIENSIS

Varuva Ashok Kumar* and C. Girish

Abstract

Thrombolysis could be a treatment to dissolve dangerous clots in blood vessels, improve blood flow, and forestall harm to tissue and organs.[1] It’s informally mentioned as clot busting for this proof. Considering this, present study was designed to investigate thrombolytic activity of the hexane and ethanol extract of Justicia traquebariensis leaves. The ethanol extract was found to have significant thrombolytic activity ((38.02±0.08) compared to the effect of Streptokinase (66.98±0.11%) used as positive control and water (3.14±0.31%) used as a negative control. Preliminary phytochemical screening of the extract showed the presence of carbohydrates, flavonoids, Quinones and Coumarins were present in leaves extract of Justicia traquebariensis one of which has thrombolytic properties.

Keywords: Thrombolysis, Justicia traquebariensis, Phytochemical screening, streptokinase.