Abstract

EVOGLIPTIN TARTRATE A NEW DRUG OF DPP-4 INHIBITOR: AN OVERVIEW

Kinjal Thakkar*, Khushbu Patel, U. B. Patel and Dr. C. N. Patel

Abstract

DPP4 inhibitors (DPP4i) are a modern class of diabetes medications that retain incretin hormones while increasing postprandial insulin secretion. Gliptins also known as DPP-IV inhibitors is a class of antidiabetic drug. DPP-IV inhibitor like Evogliptin tartrate chemically known as (3R)-4-[(3R)-3-amino- 4-(2,4,5-trifluorophenyl) butanoyl]-3- [(2-methylpropan-2-yl) oxymethyl] piperazin-2-one;(2R,3R)-2,3- dihydroxybutanedioic acid is used as a monotherapy. This article explains about chemistry, pharmacology, safety information and drugdrug interaction of Evogliptin tartrate.

Keywords: Type 2 diabetes, DPP-4 inhibitors, Classification of antidiabetics, Drug interaction.