Abstract

NIOSOMES: A PROMINENT THERAPEUTIC CARRIER MOLECULES TOWARDS TARGETED SITE

Vaishnavi Tammishetty*, Anusha Thadoju and Hyma Ponnaganti

Abstract

During the treatment of several infectious diseases there is a huge revolutionary change in the treatment of diseases from past few decades. As there is an advancement in pharmaceutical field, biotechnology not only drugs towards target site have been developed but also advancement in delivering drug towards target site has developed i.e., carriers. Drug targeting is a process in which on administration of drug substance the drug gets distributed in the body and therapeutic agents interact with targeted site without affecting the surrounding of target site. For targeted drug release there is a requirement of carriers for delivering of the drug, the novel drug delivery system plays an important role especially niosomes plays a prominent role as carriers it consists of two components mainly cholesterol and non-ionic surfactants. The niosomes are capable of delivering both hydrophilic and lipophilic drugs in a controlled manner. And it is used in treatment of several diseases like cancer, leishmaniasis, skin fungal infections, eye diseases, acne treatment, brain and CNS diseases.

Keywords: Niosomes, Drug carrier, Targeted site, Hydrophilic and Lipophilic drugs, Factors, Applications.