Abstract

PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND ANTIMICROBIAL ACTIVITY OF HERBAL OINTMENT

Kalpesh S. More*, Dr. Pankaj Chaudhari, Sachin Mahajan and Dr. Prakash Pati

Abstract

The aim of the study was assess the antimicrobial effect of some medicinal plants and its formulation against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. Medicinal plants are the important source of potentially useful structures for the development of novel chemotherapeutic agents. Historically, plants have provided a source of the development for novel drugs and plant derived drugs which have made large contributions to human health and wellbeing. The antibacterial activities of selected plants extracts were evaluated using the disk diffusion method as well as cup plate method. Zones of inhibition were observed in disc diffusion for antimicrobial investigation against Gram-positive and Gram-negative pathogenic bacteria. The Polyherbal formulation showed average zone of inhibition ranged from 6-8 mm.

Keywords: Phytochemical investigation, medicinal plant, antimicrobial activity, Polyherbal formulations, Ointment.