Abstract

DENDRIMER ARCHITECTURE: A COMPREHENSIVE REVIEW

Punya Prakash*, Krishnananda Kamath Kunjal and A. R. Shabaraya

Abstract

Dendrimers are an unique kind of polymer. They are monodisperse macromolecules with a lot of branches. Dendrimers structural advantages enable them to play a key role in nanotechnology, pharmaceutical, and medicinal chemistry. Dendrimers are ideal for a wide range of biological and industrial applications due to their unique behaviour. The bioactive agents can be easily encapsulated into the interior of the dendrimers or chemically attached that is conjugated or physically adsorbed onto the dendrimer surface, serving the desired properties of the carrier to the specific needs of the active material and its therapeutic uses. Dendrimers features, construction, drug delivery, and potential applications in numerous fields of study, technology, and therapy are all highlighted in this review. Recent breakthroughs in simplifying and improving dendrimer synthesis have resulted in a wide range of structures with lower manufacturing costs. In addition, as study improves, newer applications of dendrimers will emerge and the future should witness an higher numbers of commercialized dendrimer based drug delivery systems.

Keywords: Dendrimer, polymer, monodisperse, drug delivery.