Abstract

SCAFFOLDS - AN ADVANCED DRUG CARRIER FOR WOUND HEALING: A REVIEW

Akila R. M. and Janani M.*

Abstract

A Wound remains a challenging problem in everyday pathology due to the complex healing process. The defects found in the traditional wound dressing potentiates to development of modern dressing for tissue regeneration. Scaffolds are carriers that are used to deliver cells, drugs or growth factors on the wound site. It provides a suitable environment for cell and tissue growth and have mechanical properties innate to the original tissue. They also have wider application in repairing bone, cartilage, nerves, blood vessels, and skin. This review provides detailed summary on properties and biomaterial selection for fabrication of scaffold. This article provides and overview on the fabrication of scaffold along with surface modification techniques. In addition, the details of marketed scaffolds have been provided. Finally, future outcome of these scaffolds is presented.

Keywords: Scaffolds, wound healing, skin tissue engineering, 3D printing, biomaterials, electrospinning.