Abstract

GUILLAIN-BARRE SYNDROME - IN BRIEF

Dr. Anjana Tom, Dr. Manasa R., Dr. Aksa Johnson and Dr. Presly Thomas Augustine

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Abstract

The Guillain-Barre Syndrome (GBS) is a life-threatening postinfectious disease characterised by rapidly progressive, symmetrical weakness of extremities and acute areflexic paralysis with albuminocytologic dissociation (i.e., high levels of protein in the cerebrospinal fluid). Guillain-Barre syndrome is the m ost common and most severe acute paralytic neuropathy, with about 10,0000 people developing the disorder every year worldwide. Under the umbrella term of Guillain-Barre syndrome, there are several recognisable variants with distinct clinical and pathological features. The clinicopathological classification suggests AIDP, AMAN, AMSAN, and Miller Fisher Syndrome which affects the cranial nerves. The symptoms progress very rapidly. In some people, the disease becomes serious in just a few hours. Treatment can help reduce the severity of symptoms and shorten the duration of the illness.

Keywords: Guillain-Barre Syndrome, Clincopathological classification, Pathogenesis, Clinical features, Diagnosis, Management.