Abstract

A STUDY TO IDENTIFY POTENTIAL DRUG RELATED PROBLEMS AFFECTING THE QUALITY OF LIFE IN TYPE 2 DIABETES MELLITUS PATIENTS IN TERTIARY CARE TEACHING HOSPITAL

Satish S., Keerthana Sajith* and A.R. Shabaraya

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Abstract

Drug related problems (DRPSs) commonly occur in many Type2 Diabetes Mellitus patients. The purpose of the study was to assess DRP’s and factors associated with its occurrence. The present study involved 100 patients with Type II Diabetes Mellitus which was conducted at a tertiary care hospital in Mangalore. Participants met inclusion criteria were selected for the study. DRP’s were collected by using standard data collection form. Analysing the co morbidities, it was found that out of 100 patients, 50% of patients had only Diabetes Mellitus whereas other 50% had other comorbidities viz. Hypertension (20%), Foot ulcer (15%), Breathlessness (5%), Cholesterol (4%), analysing their DRP’s it was found that receiving no little of the drug (78%) was the reason for major DRP, taking too low dose would may not be strong enough to get beneficial or therapeutic effects. In terms of receiving the wrong drug (31%), 9 irrational drugs (viz. statins, pantoprazole, rabeprazole), 5 drugs were inappropriate (viz. calcium channel blockers, glimepiride), 2 drugs were ineffective (viz. Spironolactone) were found. 48% of the patients experienced an ADR of which mild cases (48%), moderate cases (52%) were identified. In case of nonadherence (4%), the factors found were fear and worry (1%), misunderstanding (2%) and lack of symptoms (1%) were seen. Receiving too much of the drug (12%), including prescription drugs can result in an overdose. Other factors analyzed in the study for DRP’s includes not receiving an indicated drug and receiving too little of the drug (fear, cost, misunderstanding, lack of symptoms) were the factors seen. For receiving the wrong drug, the factors were irrational, inappropriate and ineffective. Mild, Moderate, severe, lethal characteristics were found in patients experiencing an ADR. The present study had total of 200 DRPs. It can be concluded that patients had minor DRPs which are controllable. Early identifications of DRP’s and factors associated with them are essential to prevent, resolve DRP’s in Type II Diabetes Mellitus.

Keywords: DRP’S, Type II Diabetes Mellitus, Quality of Life (QOL).