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Abstract

A SYSTEMIC REVIEW ON THE SAFETY OF COVID 19 VACCINES AVAILABLE TODAY

Tasnim Nazeer*, Jisna K. Philip, Karthika Lal. B., Subash Chandran M. P. and Prashob G. R.

Abstract

A world wide competition for the development of Covid 19 vaccines was raised due to the wide spread of SARS-CoV-2 and the resulting pandemic situation. The first two vaccines were approved which was based on the mRNA vaccine platform and were developed by Pfizer/BioNTech and Moderna in December 2020. It is found that there is high efficacy rates of 94-95 % after two interval doses, with limited side effects and a low rate of adverse reactions. After that, development of different type of vaccines against Covid 19 occurred world wide. Due to the rapid pace of vaccine development and the uncertainty of potential long-term adverse effects, raised some level of hesitation against Covid 19 vaccines within the global community. Currently the development of vaccines for the prevention of infection with the SARS- CoV-2 has been a success, with no serious concerns identified in the ongoing phase 3 clinical trial. Minor local side effects such as pain, redness, and swelling have been observed with the vaccines. Some of the systemic symptoms experienced were fever, fatigue, headache, and muscle and joint pain, and most have occurred during the first 24 to 48 hours after vaccination.

Keywords: SARS-CoV-2, COVID-19 vaccine, COVID-19 pandemic.


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