Abstract

AN OVERVIEW ON MICROWAVE ASSISTED SYNTHESIS OF ANTIMALARIAL COMPOUNDS

Abhishek Chaudhary, Divya Arora* and Pooja Devi

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Abstract

The present review article offers a detailed account of the microwave irradiation synthesis of novel ligands for antimalarial potential. Microwave synthesis being an economical method, time saving and environmental friendly will be best suitable for future of antimalarial drugs. The synthesis by microwave irradiation and antimalarial studies of various drugs as per the future need of medical and pharmaceuticals have been discussed. Some of the derivatives synthesised by microwave irradiation method discussed here includes: benzothiazolespirooxindole derivatives; pyrimidine derivatives; 4-benzyloxy- and 4- aryloxy-2 trichloromethylquinazolines; 2, N6-disubstituted 1,2- dihydro-1,3,5-triazine-4,6-diamines; 4-aminoquinolines; etc.

Keywords: Malaria, Microwave irradiation, Antimalarial potential.