Abstract

IMPACT OF COVID-19 IN ALZHEIMER’S PATIENT’S

Swathy N. S.*, Mobin P. Chacko, Prasobh G. R. and Grace N. Raju

.

Abstract

Due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV- 2) causes Alzhemer’s disease a neurological complication of COVID- 19. In AD patients multiple pathological changes such as the excessive expression of viral receptor angiotensin converting enzyme 2 and proinflammatory molecules may increase morbidity and mortality of covid 19. various neurologic symptoms like cognitive impairment has reported in covid 19 that may results in AD, SARS-CoV-2 may invade into the central nervous system, COVID-19- may induce inflammation, long-term hospitalization and delirium, and post-COVID-19 syndrome. In addition, uninfected AD patients behavioral symptoms may be worsen by covid 19 crisis and provide new challenges for AD prevention. In this review.we first know about the SARS-CoV-2 and AD-COVID-19.

Keywords: COVID-19, SARS-CoV-2, Alzheimer’s disease, Inflammation, Central nervous system.