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Abstract

ASSESSMENT OF THE EFFICACY AND SAFETY OF SNEC 30 (CURCUMA LONGA) CAPSULES IN THE TREATMENT OF TYPE 2 DIABETES: AN OPEN LABEL, PROSPECTIVE, COMPARATIVE, RANDOMIZED STUDY

Narsingh Verma, Vandana Awasthi, Smriti Rastogi*, Abhinav Verma, Saurabh Arora and Neha Arora

Abstract

Background: Diabetes mellitus (DM) is a chronic metabolic disorder wherein a person has excessive concentrations of blood sugar. Several studies have demonstrated inconsistent effects of curcumin on glycemic outcomes and lipid parameters in patients with prediabetes and type 2 diabetes mellitus (T2DM). This study aimed to assess the effect of curcumin on glycemic control in T2DM subjects. Methodology: A total number of 80 patients of either sex between the age group 18 to 65 years (both inclusive) having type 2 diabetes were recruited in the study. At Day 0 subjects were randomized for ongoing conventional treatment or SNEC 30 Capsule co-administered with the conventional treatment. Study specific tests like Hba1c, Post Prandial glucose and other biochemistry and hematology tests were performed at the screening and at the end of study duration (3 Months). Results: Out of 80 patients with Type 2 diabetes that were randomized for the study, 59 patients were male and 21 were female. Among 80 subjects, 69 subjects completed the study and 11 subjects dropped-out (05 from SNEC 30 group and 06 subjects from conventional group). When SNEC 30 group (35 patients) (Arm A) was compared with group that received conventional treatment (Arm B=34 patients), it was observed that post-treatment decrease in values of Hb1Ac and blood glucose levels recorded, was significantly higher (p

Keywords: Type 2 diabetes, SNEC 30, Curcuma Longa, HbA1c.


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