Abstract

SCREENING OF ANTIHYPERLPIDEMIC ACTIVITY ON WHOLE PLANT OF PAVONIA ODORATA WILLD

Neethu Krishnan S.*, Meera Bhaskaran, Mohammed Shihab K.K., Fathima Suman P. and Harsha C.T.

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Abstract

Pavonia odorata Willd is a medicinal plant found in the moist deciduous forest region of the world where it is used by local people to treat fever, dysentery, ulcers and bleeding disorders. The present study is aimed at investigating the antihyperlipidemic activity on methanolic extract of P.odorata Willd. The preliminary phytochemical screening of the methanolic extract showed presence of alkaloids, phenolic compounds, steroids, mucilage and flavonoids. The antihyperlipidemic activity was determined through Oil Red O Staining technique. Throughout the studies the plant extract showed potent antihyperlipidemic activity and the activity was found to be concentration dependent which may be attributed to the various phyto constituents of the plant.

Keywords: Pavonia odorata Willd, Antihyperlipidemia, Oil Red O Staining, 3T3L1 Pre adipocyte cells.