Abstract

ANTIDIABETIC ACTIVITY OF MAGIC HERB GILOE: A REVIEW

Pooja Devi, Abhishek Chaudhary*, Pritam Ram Sharma and Divya Arora

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Abstract

Tinospora cordifolia (Guduchi) is a perennial climber that is evergreen. This deciduous and dioecious plant belongs to the family Menispermaceae. It is a plant of significant medicinal importance in the Indian system and designated as Rasayana. The current medical establishment has acknowledged its efficacy as well. The stem is approved for use in medicine, however the entire plant is used medicinally. This is due to the stems having a higher alkaloid content than the leaves. The plant mainly contains alkaloids, glycosides, steroids, diterpenoid lactones, sesquiterpenoid, aliphatic compound and other miscellaneous compound. The purpose of this review is to emphasise giloy's anti-diabetic properties. Currently current traditional diabetic mellitus treatments have their own set of limitations, thus researchers are looking for alternatives from medicinal plants with antihyperglycemic properties to fill the gap. Tinospora cordifolia's antidiabetic benefits are well-known in Ayurveda and even in recent modern studies. Several studies on its extracts (such as immune-modulatory, anti-hyperglycemic, antioxidant, adaptogenic, hepatoprotective, hormone regulator, and so on) and isolated phytoconstituents (such as tinosporin, berberine, jatrorrhizine, and so on) have reported that it is a preventive and curative antidiabetic herb, which has been supported by clinical trials.

Keywords: Diabetes mellitus, Guduchi, Herbal remedies, Tinospora cordifolia, Traditional medicine.