Abstract

NATURAL POLYMERS USED AS BINDER IN PHARMACEUTICAL INDUSTRY AND RESEARCH- A REVIEW

Chinu Kumari*, Rishabh Bedi, Shivali Singla, Hitesh Thakur, Sachin Goyal and Sunita Devi

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Abstract

Binders are commonly known to use as cohesiveness to the granules for making of tablets. Tablet may intact after compression. New excipients may formed to use as binding agent in formulations of tablets. Various binding agents may be useful to form various tablet strengths and properties of drug release for different pharmaceutical perspectives. Some natural polysaccharides may be highly used in the pharmaceutical industries and food industries as excipients and additives too because it has low toxicity, biodegradable availability and low cost. Natural binders like various starches, gums, mucilages and dried fruits have strong binding capacity as compare to others such as disintegrants, filler, sustain release, and these polymers are most safest than polymers like PVP. Various starches like rice, potato, maize, corn, wheat, tapioca starch and gums like ferula gummosa boiss, gum olibanum, beilschmiedia seed gum, okra gum, aegle marmelos gum, gum cordial, okra gum and cassia roxburghii seeds gum and plant fruit like date palm fruit and orange peel pectin has been shows best potency as a binding agent.

Keywords: Excipients; Polymer; Granule; Tablet; Gum.