Abstract

A REVIEW ON MUCORMYCOSIS

Dhruvi Kasvala*, Priyanshi Monpara, Prof. Pooja Patel and Dr. Umesh Upadhyay

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Abstract

The Zygomycetes class is divided into two orders: Mucorales and Entomophthorales. These two orders create infections that are significantly different. Mucormycosis is an angioinvasive infection caused by Mucorales genera (Rhizopus, Mucor, Rhizomucor, Absidia, Apophysomyces, Cunninghamella, and Saksenaea). Mucormycosis can affect the rhino-orbito-cerebral region, the lungs, the skin, or the gastrointestinal tract. Immune-compromising disorders include haematological malignancies, bone marrow or peripheral blood stem cell transplantation, neutropenia, solid organ transplantation, diabetes mellitus with or without ketoacidosis, corticosteroids, and deferoxamine therapy for iron overload.A satisfactory outcome requires early identification, treatment of the underlying medical issue, surgery, and the use of an amphotericin B product. The order's genera In immunocompetent people, the entomophthorales cause entomophthoramycosis, a chronic subcutaneous infection. Tropical and subtropical regions are conducive to the spread of this virus. Basidiobolus is a genus of bacteria that causes a chronic subcutaneous infection of the thigh, buttock, and/or trunk. It has been observed that it occasionally affects the gastrointestinal tract. A persistent infection of the nasal submucosa and subcutaneous tissue of the nose and face is caused by the genus Conidiobolus. The clinical manifestations will be discussed in this study.

Keywords: Mucormycosis, entomophthoramycosis, zygomycetes, Mucorales, Entomophthorales, Mucor, Rhizopus, Apophysomyces, Conidiobolus, Basidiobstud.