Abstract

PRESCRIBING PATTERN OF DRUGS IN CORONARY ARTERY DISEASE PATIENTS: A PROSPECTIVE OBSERVATIONAL STUDY

Syeda Juveria Sultana*, Md Yousuf Hussain, Syeda Batool, Sai Prakash, Dr. Kanchana N. Dussa and Dr. Mehraj Unnisa

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Abstract

Coronary artery disease also called as ischemic heart disease or coronary heart disease is mainly caused due to atherosclerosis of inner lining of the vessels (plaque buildup in coronary artery walls) that supply blood to the heart. A prospective observational study was conducted in an inpatient department of cardiology in a tertiary care hospital. The duration of the study was 4 months i.e., from October 2018 to January 2019. Ninety-one patients were enrolled in the study of which 64(70.3%) were male and 27(29.7%) were female. Maximum patients belonged to the age group of 51-60years in which 28(30.8%) were male and 8(8.8%) were female. Among co-morbid conditions hypertension and diabetes mellitus were most commonly observed in patients. In this study, Most commonly prescribed cardiovascular single drugs were anti-hypertensives(26.06%) followed by antiplatelets(25.17%) and commonly prescribed cardiovascular FDCs were combination of antihypertensive drugs (46.43%) followed by combination of antiplatelet drugs (30.36%). The average number of drugs per prescription was 9.23. Antibiotics were prescribed to 31.90 % patients and injection was prescribed to 68.10% patients. Cardiovascular drugs prescribed from the 2017 WHO model list of essential medicines were 34.26%. Among drug-drug interactions, moderate interactions were most commonly found followed by major interactions. Present study results indicate that pharmacist and physician can work in collaboration to bring better patient outcomes.

Keywords: Prescribing pattern, coronary artery disease, WHO prescribing indicators, cardiovascular drugs, polypharmacy, drug-drug interactions.