Abstract

DIAGNOSIS OF ENDOMETRIAL TUBERCULOSIS AMONG FEMALES WITH MENSTRUAL DYSFUNCTION ON ENDOMETRIAL HISTOPATHOLOGY

Shaista Rashid*, Shazia Naseeb and Muhammad Adil Ramzan

.

Abstract

Background: Tuberculosis is a major health concern worldwide. Pakistan accounts highest global burden of tuberculosis. One of the millennium development goals aspire to reduce the burden of tuberculosis. The aim of study was to find out the frequency of endometrial tuberculosis on endometrial histopathology in women who underwent endometrial biopsy. Objective: To determine the frequency of endometrial tuberculosis on endometrial histopathology in women who had endometrial biopsy for evaluation of menstrual dysfunction. Methods: A prospective cross-sectional study was conducted at Abbasi Shaheed Hospital, Karachi, Pakistan during Jan 2019 to Dec 2020. A total 129 reproductive female included in study presented with menstrual dysfunction between 20-45 years after taking informed consent. In all women premenstrual endometrium biopsy was taken for histopathology by diagnostic curettage. Results were analyzed on SPSS version 20; frequency and percentage were calculated for demographic characteristic, clinical symptoms and biopsy result. Association was calculated for clinical menstrual symptoms and histopathology with p –value >0.05 was taken as significant. Results: In our study 129 females with menstrual symptoms was included. The mean age of females was 36.15±4.41 years. The commonest presenting symptoms were heavy menstrual bleeding 69.8%.Out of 129 females, only one patient (0.8%) found positive for tuberculosis on histopathology. Conclusion: Diagnosis of endometrial tuberculosis in women with menstrual symptom on histopathology is small but significant. Female endometrial tuberculosis should be considered for exclusion if the patient presents with menstrual symptoms.

Keywords: Genital tuberculosis, endometrial histopathology, menstrual irregularities.