Abstract

PREVALENCE OF DYSLIPIDEMIA IN SUDANESE PATIENTS WITH TYPE TWO DIABETES MELLITUS: A CROSS SECTIONAL STUDY

Ahmed M. Ahmed* and Amna M. Ibrahim

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Abstract

Dyslipidemia is a leading factor for cardiovascular disease (CVD) which is remains a leading cause of morbidity and mortality worldwide. In this is a cross sectional study a total of 80 T2DM patients were enrolled and compared to 50 control healthy subjects, fasting blood samples were collected and biochemical parameters include blood glucose, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, Apo A1, ApoB, Lp(a) and MDA were measured. The prevalence of dyslipidemia was high in patients group compared to controls (P < 0.01). Blood glucose and HbA1c showed significant increase in patients compared to control (P < 0.01). In addition, lp(a) and MDA, LDL and apoB were higher in patients than control (P < 0.05). Moreover, dyslipidemia was high in CHD patients, long period and smokers (P < 0.01); and TC, LDL, HDL and lp(a) were higher in CHD patients than other patients (P < 0.01). Additionally, lp(a) was high in smokers and long period (P < 0.01). LDL was found the main increased profile. Dyslipidemia is high prevalent in T2DM in this study, dyslipidemia was high in patients with history of CHD, smokers and increased with long period. Continuous and regular measurements of lipids is essential and helping to reduced risk for CVD.

Keywords: Dyslipidemia, lipids, T2DM, CVD.