Abstract

ANTIBACTERIAL ACTIVITY OF CINNAMOMUM BURMANII STEM BARK EXTRACT AGAINST STAPHYLOCOCCUS XYLOSUS

Sri Agung Fitri Kusuma*, Ana Indrayati, Mulyati and Danni Ramdhani

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Abstract

Objective: this study was aimed to evaluate the antibacterial activity of Cinnamomum Burmanii stem bark ethanolic extract against Staphylococcus xylosus ATCC 3342. Methods: The Cinnamomum ethanolic extract was obtained from a maceration process using 70% ethanol as the solvent. The thick extract then analyzed to detect secondary metabolites using the standard method. The antibacterial activity was done by the agar diffusion method and compared to tetracycline HCl as the antibiotic standard. Followed by the determination of minimum inhibitory concentration of the extract using the macrodilution method. Results: The phytochemical analysis of the C. Burmanii stem bark extract revealed that it contained of alkaloids, tannins, flavonoids, saponins and steroids. The antibacterial activity of the extract on S. xylosus was stronger as the increasing of the extract concentration. However, in comparison with tetracycline HCl, the antibacterial activity of the extract was lower. The MIC value of the extract against S. xylosus was 0.875

Keywords: Cinnamomum Burmanii, stem, extract, antibacterial, Staphylococcus xylosus.