Abstract

ISOLATION, STRUCTURAL ELUCIDATION AND BIOLOGICAL ACTIVITY OF THE FLAVONOID FROM THE LEAVES OF JUNIPERUS PHOENICEA

Kutaib Ibrahim Alzanda*, Dara Muhammed Aziz, Mukul Tailang

Abstract

New flavonoid (1) was isolated from ethanol extract of the leaves of Juniperus phoenicea by preparative thin-layer chromatography technique. The leaves alcoholic extract of J. phoenicea dose dependently inhibited the growth of Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. The structure of compound 1 was elucidated on the basis of MS, IR, UV, 1H NMR and 13C NMR spectroscopic data, including 2D NMR experiments to be 1-(3,4-dihydro-3,5,7-trihydroxy-2,2-dimethyl-2H-1-benzopyran-6- yl)-3-(4-hydroxyphenyl)- -propen-1-one.

Keywords: Isolation, Structural Elucidation, Phytochemical, Flavonoids, Juniperus phoenicea.