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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

ISOLATION, STRUCTURAL ELUCIDATION AND BIOLOGICAL ACTIVITY OF THE FLAVONOID FROM THE BARKS OF JUNIPERUS PHOENICEA

Kutaib Ibrahim Alzanda*, Mohamed Ali Abdullah, Mukul Tailang

Abstract

New flavonoid (1) was isolated from ethanol extract of the barks of Juniperus phoenicea by preparative thin-layer chromatography technique. The barks alcoholic extract of J. phoenicea dose dependently inhibited the growth of Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. The structure of compound 1 was elucidated on the basis of MS, IR, UV, 1H NMR and 13C NMR spectroscopic data, including 2D NMR experiments to be 1-[2,4- dihydroxy-3-(2-hydroxy-3-methyl-3-butenyl)-6-methoxyphenyl]-3-(4- hydroxyphenyl)-2-propen-1-one.

Keywords: Isolation, Structural Elucidation, Phytochemical, Flavonoids, Juniperus Phoenicea.

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