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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

ISOLATION, STRUCTURAL ELUCIDATION AND BIOLOGICAL ACTIVITY OF THE FLAVONOID FROM THE ROOTS OF CUDRANIA TRICUSPIDATA

Kutaiba Ibrahim Alzand*, Mohamed Ali Abdullah, Mukul Tailang

Abstract

New flavonoid (1) was isolated from ethanol extract of the roots of Cudrania tricuspidata by preparative thin-layer chromatography technique. The roots alcoholic extract of Cudrania tricuspidata dose dependently inhibited the growth of Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. The structure of compound 1 was elucidated on the basis of MS, IR, UV, 1H NMR and 13C NMR spectroscopic data, including 2D NMR experiments to be 5,7,4'- Trihydroxy-6-prenylflavanone.

Keywords: Isolation, Structural Elucidation, Phytochemical, Flavonoids, Cudrania tricuspidata.

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