Abstract

CASE REPORT ON PHENYTOIN SHOWS SKIN REACTIONS (PURPURIC ERUPTION) IN A TERTIARY CARE REFERRAL HOSPITAL- KERALA

Mr.Shibil.PK*, Linu Mohan.P, Shinu.C, Mohammed Fazil R.M, Mammen Paul.

Abstract

Phenytoin is an antiepileptic drug. It is useful to treat partial seizures and generalized tonic-clonic seizures but not primary generalized seizures such as absence seizures or myoclonic seizures. We report a case on phenytoin that shows skin reactions (purpuric eruption). A 27 years old male patient admitted in neuro surgery department of the hospital for the treatment of head injury, with multiple wound over forehead, upper lip, lower lip, and left side chest. The causality of the event assessed as per WHO-UMC for standardized case causality assessment criteria can be considered as probable. Analyzed by Naranjo’s ADR probability scale, the score was 5, which also make it a probable event.

Keywords: Phenytoin, tonic-clonic seizures, ADR probability scale.